Articles

  1. Prenatal Nutrition:Nutrient recommendations Before, During & After Pregnancy Download Article

    Govind shukla, Shivani prashar, M.sarika, Dr.Sunil Yadav, Dr.V.Chandramouli, C.J. Sampath kumar
    • Article Type: Review Article
    • View Abstract
    • Pages (1-7)
    • No of Download = 409

    Abstract

    close

    Nutrition before and during pregnancy has a profound effect on the development of infants. This is a rather critical time for healthy fetal development as infants rely heavily on maternal stores and nutrient for optimal growth and health outcome later in life. Prenatal nutrition addresses nutrient recommendations before and during pregnancy. Birth weight of the newborn at delivery reflects the sufficiency and the quality of maternal nutrient for the fetus during pregnancy. Prenatal nutrition has a strong influence on birth weight and further development of the infant. The present paper reviews the role of prenatal nutrition in pregnancy. KEYWORDS: Prenatal nutrion, Pregnancy, Foetal development during pregnancy.

  2. A Questionnaire based Survey on Awareness of Clinical Trials among General Population. Download Article

    Balasubramanian J, Rukmani A, Rajesh kumar R, Purushothaman K.
    • Article Type: Research Article
    • View Abstract
    • Pages (8-17)
    • No of Download = 504

    Abstract

    close

    The aim of the questionnaire based survey was to find the extend of awareness of clinical trials among general population among the different category of people in Chennai. The project was carried out among the general population living in and around Chennai. While recruiting the subjects care was taken to include different strata of the society and the informed consent was obtained from each subject before starting the study The participants was provided with the “Evaluation tool to assess the perception of clinical trials among general population”. KEY WORDS: Clinical trial, History of clinical research.

  3. Evaluation of anti-diabetic potential of leaves of Nelumbo nucifera in streptozotocin-induced diabetic rats Download Article

    Nallani Venkata Rama Rao, A.Narendra Babu, M.Sathish Kumar, P.Sharmila Nirojini, Venkatarao Vutla, Ramarao Nadendla
    • Article Type: Research Article
    • View Abstract
    • Pages (18-24)
    • No of Download = 211

    Abstract

    close

    Nelumbo nucifera Gaertn. (Nymphaeaceae), also known as sacred lotus, is a well known medicinal plant. Nelumbo nucifera (family Nymphaeaceae) are free floating plants.The methanolic extract of Nelumbo nucifera leaves was obtained by soxhlet extraction apparatus. The extract was subjected to preliminary phytochemical screening by using standard procedures.The toxicity studies and dose fixation were carried out by using OECD 425 guideline. According to OECD 425 guideline toxicity study no toxic symptoms were observed up to dose 2000 mg/kg.The anti diabetic effect of Nelumbo nucifera leaf methanolic extract given in streptozotocin induced diabetic rats. Oral administration of methanolic extract for 15 days in diabetic mice exhibits highly significant (P < 0.01) antidiabetic activity and also alters the body weight significantly . The data were analyzed using analysis of variance followed by Dunnett's test.The observations confirm that methanolic extract of NELUMBO NUCIFERA leaf and stem has antidiabetic activity due to presence of alkaloids,aminoacids, saponins, glycosides, triterpenoid, vitamins etc There is a need of further investigation to isolate and identify the principle chemical constituents for its anti diabetic property.

  4. Highly Active Antiretroviral Therapy: Incidence of Adverse Drug Reactions Download Article

    Languluri Reddenna, Shaik Ayub Basha, Donthu Venu Gopal, Tedlla Rama Krishna
    • Article Type: Research Article
    • View Abstract
    • Pages (25-30)
    • No of Download = 301

    Abstract

    close

    The Acquired Immunodeficiency Syndrome (AIDS) was first recognized in 1981, in the United States of America in young homosexual men who had Kaposi sarcoma and serious infections. HIV is transmitted through unprotected sexual intercourse, transfusion of contaminated blood, sharing of contaminated needles and between a mother and her infant during pregnancy, childbirth and breastfeeding. In India, an estimated 0.1 percent of adults aged 15-49 are living with HIV, which seems low when compared to HIV prevalence in some parts of sub- Saharan Africa.The HIV prevalence at antenatal clinics was 1% in 2007. This number is smaller than the reported 1.26% in 2006, but remains the highest out of all states. HIV prevalence at STD clinics was very high at 17% in 2007.Although adverse reactions are common and often predictable, their management must be individualized.In addition, the patient's report of severity can be inconsistent with the clinical interpretation and this must be considered when determining the management of adverse reactions.Antiretroviral therapy is effective for HIV treatment but also increasingly complex. The many adverse effects of therapy may cause symptoms affecting a variety of organ systems. Patient non adherence is the reason for the treatment failure for antiretroviral therapy. To optimize adherence treating physicians must focus on early detection and prevention of ADRs, when possible and distinguishing those that are self-limited from those that are potentially serious. The pharmacist should be able to detect ADRs and the culture of reporting ADRs should be instructed. All ART centers should have Pharmacovigilance cell. All ADRs reported should be analyzed as per WHO guidelines on causal assessment. Our study concluded that there is a need of the active Pharmacovigilance Centre with intensive monitoring for ADRs by the Pharmacist in Indian HIV positive patients.

  5. Pachygyria: A Neurological Migration Disorder Download Article

    Rajesh Kumar.D, Ramu.V.V, Ram Sarath Kumar.B, Sumalatha.N3 Murali.G, Prathap Reddy.P
    • Article Type: Review Article
    • View Abstract
    • Pages (31-33)
    • No of Download = 697

    Abstract

    close

    Pachygyria is a neuronal migration disorder characterized by thick convulsions on cerebral cortex and brain has few gyri. It leads to mental retardation. It is also known as Macrogyria. It is considered as a rare disease. The disease involves mutations in a number of genes. Mainly the symptoms are seizures and delayed development. MRI and CT scan are used for diagnosis. It can be treated by anti epileptic medication and various therapies like speech therapy and occupational therapy. G therapy is effective for the treatment. So far, there is no specific drug treatment.

  6. A Review on Amnesia Download Article

    Rajesh Kumar.D, Ramesh.V, Vinod Kumar.P, Vijay Kumar.K, Swaminaidu.P
    • Article Type: Review Article
    • View Abstract
    • Pages (34_37)
    • No of Download = 312

    Abstract

    close

    Amnesia means loss of memory sometimes including the memory of personal identity due to brain injury, shock, fatigue, repression or illness. The main cause of Amnesia is brain damage. There are six different types of amnesia includes anterograde amnesia, retrograde amnesia, Transient Global Amnesia, Dissociative amnesia, Infantile amnesia, Wernike-Korsakoff's psychosis. Physical examination, Cognitive tests and Imaging tests are used for diagnosis of amnesia. Treatment includes Cognitive therapy, Psychotherapy and occupational therapy.

Registered and Approved by National Science Library (NSL),National Institute of Science Communication And Information Resources(NISCAIR),
Council of Scientific and Industrial Research,New Delhi, India"